Pharma Cogenetics
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P127H - Human HLA-B 5801 Drug Hypersensitivity Gene Detection Kit
Human Leukocyte Antigens (HLA) play a key role in the development of severe immune-mediated adverse drug reactions. Multiple phenotypically distinct immune-mediated adverse drug reactions have been associated in particular with the carriage of specific HLA class I risk alleles.
For Asians, especially the Han people, HLA-B*5801 is highly related to an allergy to allopurinol, a commonly used drug for the treatment of gout and hyperuric acid. Individuals with the genetic marker HLA-B*5801 have a much higher risk of blindness, death, and Stevenson-Jonson syndrome after taking this drug. Therefore, testing whether the HLA-B*5801 allele is carried can reduce the risk of SJS/TEN induced by allopurinol in patients.Allopurinol Hypersensitivity Gene Test Allopurinol Hypersensitivity Gene Test Kit HLA-B 5801 Drug Hypersensitivity Gene Test KitEmail Details
